MediaSport.id – Manchester United akan langsung menghadapi Chelsea di pekan pembuka Premier League 2018/19. Laga berat juga akan mereka jalani pada pekan ke-9 kala bertandang ke rival Liverpool. Sedangkan, derby Manchester baru akan terjadii bulan Desember 2019.
Pada Boxing Day, Setan Merah akan menghadapi Newcastle United di laga tandang. Berikut jadwal lengkapnya:
*Jadwal masih bisa berubah dikarenakan pengaturan hak siar atau jadwal laga kompetisi lainnya.
| Agustus 2019 |
| 11/8 vs Chelsea (K) |
| 17/8 vs Wolverhampton Wanderers (K) |
| 24/8 vs Crystal Palace (K) |
| 31/8 vs Southampton (T) |
| September 2019 |
| 14/9 vs Leicester City (K) |
| 21/9 vs West Ham United (T) |
| 28/9 vs Arsenal (K) |
| Oktober 2019 |
| 5/10 vs Newcastle United (K) |
| 19/10 vs Liverpool (T) |
| 26/10 vs Norwich City (T) |
| November 2019 |
| 2/11 vs Bournemouth (T) |
| 9/11 vs Brighton and Hove Albion (H) |
| 23/11 vs Sheffield United (T) |
| 30/11 vs Aston Villa (K) |
| Desember 2019 |
| 3/12 vs Tottenham Hotspur (K) |
| 7/12 vs Manchester City (T) |
| 14/12 vs Everton (H) |
| 21/12 vs Watford (T) |
| 26/12 vs Newcastle United (K) |
| 28/12 vs Burnley (T) |
| Januari 2020 |
| 1/1 vs Arsenal (T) |
| 11/1 vs Norwich City (K) |
| 18/1 vs Liverpool (T) |
| 21/1 vs Burnley (K) |
| Februari 2020 |
| 1/2 vs Wolverhampton Wanderers (K) |
| 8/2 vs Chelsea (T) |
| 22/2 vs Watford (K) |
| 29/2 vs Everton (T) |
| Maret 2020 |
| 7/3 vs Manchester City (K) |
| 14/3 vs Tottenham Hotspur (T) |
| 21/3 vs Sheffield United (K) |
| April 2020 |
| 4/4 Brighton and Hove Albion (T) |
| 11/4 Bournemouth (K) |
| 18/4 Aston villa (T) |
| 25/4 Southampton (K) |
| Mei 2020 |
| 2/5 vs Crystal Palace (T) |
| 9/5 vs West Ham United (K) |
| 17/5 Leicester CIty (T) |